Low molecular mass peptide dendrimers that express antimicrobial properties

被引：45

作者：

Janiszewska, J

Swieton, J

Lipkowski, AW

Urbanczyk-Lipkowska, Z

机构：

[1] Polish Acad Sci, Inst Organ Chem, PL-01224 Warsaw, Poland

[2] Polish Acad Sci, Med Res Ctr, PL-02106 Warsaw, Poland

[3] Ind Chem Res Inst, PL-01793 Warsaw, Poland

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2003年 / 13卷 / 21期

关键词：

D O I：

10.1016/j.bmcl.2003.08.009

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A series of low-generation dendrimeric peptides was synthesized in an attempt to evaluate their antimicrobial potency. All tested dendrimeric peptides in which lysine was a starting and branching element expressed moderate activity against Staphylococcus aureus NCTC 4163, and Escherichia coli NCTC 8196. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：3711 / 3713

页数：3

共 15 条

[1] Quaternary ammonium functionalized poly(propylene imine) dendrimers as effective antimicrobials: Structure-activity studies [J].