Direct reductive amination of aldehydes and ketones using phenylsilane: Catalysis by dibutyltin dichloride

被引：166

作者：

Apodaca, R ^{[1
]}

Xiao, W ^{[1
]}

机构：

[1] RW Johnson Pharmaceut Res Inst, San Diego, CA 92121 USA

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 11期

关键词：

D O I：

10.1021/ol015948s

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A procedure for direct reductive amination of aldehydes and ketones was developed which uses phenylsilane as a stoichiometric reductant and dibutyltin dichloride as a catalyst. Suitable amines included anilines and dialkylamines but not monoalkylamines.

引用

页码：1745 / 1748

页数：4

共 30 条

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