Evolutionary dynamics of an Arabidopsis insect resistance quantitative trait locus

被引：193

作者：

Kroymann, J ^{[1
]}

Donnerhacke, S ^{[1
]}

Schnabelrauch, D ^{[1
]}

Mitchell-Olds, T ^{[1
]}

机构：

[1] Max Planck Inst Chem Ecol, Dept Genet & Evolut, D-07745 Jena, Germany

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2003年 / 100卷

关键词：

D O I：

10.1073/pnas.1734046100

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Glucosinolate profiles differ among Arabidopsis thaliana ecotypes, caused by the composition of alleles at several glucosinolate biosynthetic loci. One of these, GS-Elong, harbors a family of methylthioalkylmalate synthase (MAM) genes that determine the side chain length of aliphatic glucosinolate structures. Fine mapping reveals that GS-Elong constitutes an insect resistance quantitative trait locus, caused by variation in glucosinolate profiles conferred by polymorphism of MAM alleles in this region. A sequence survey of randomly chosen ecotypes indicates that GS-Elong is highly variable among A. thaliana ecotypes: indel poly-morphisms are frequent, as well as gene conversion events between gene copies arranged in tandem. Furthermore, statistical methods of molecular population genetics suggest that one of the genes, MAM2, is subject to balancing selection. This may be caused by ecological tradeoffs, i.e., by contrasting physiological effects of glucosinolates on generalist vs. specialist insects.

引用

页码：14587 / 14592

页数：6

共 46 条

[1] Nucleotide sequence variation at two genes of the phenylpropanoid pathway, the FAH1 and F3H genes, in Arabidopsis thaliana
Aguadé, M
[J]. MOLECULAR BIOLOGY AND EVOLUTION, 2001, 18 (01) : 1 - 9
[2] Evolutionary dynamics of plant R-genes
Bergelson, J
Kreitman, M
Stahl, EA
Tian, DC
[J]. SCIENCE, 2001, 292 (5525) : 2281 - 2285
[3] Rapid concerted evolution via gene conversion at the Drosophila hsp70 genes
Bettencourt, BR
Feder, ME
[J]. JOURNAL OF MOLECULAR EVOLUTION, 2002, 54 (05) : 569 - 586
[4] ALLYLGLUCOSINOLATE AND HERBIVOROUS CATERPILLARS - CONTRAST IN TOXICITY AND TOLERANCE
BLAU, PA
FEENY, P
CONTARDO, L
ROBSON, DS
[J]. SCIENCE, 1978, 200 (4347) : 1296 - 1298
[5] CHARLESWORTH B, 1993, GENETICS, V134, P1289
[6] α-keto acid elongation and glucosinolate biosynthesis in Arabidopsis thaliana
de Quiros, HC
Magrath, R
McCallum, D
Kroymann, J
Scnabelrauch, D
Mitchell-Olds, T
Mithen, R
[J]. THEORETICAL AND APPLIED GENETICS, 2000, 101 (03) : 429 - 437
[7] Quantifying the slightly deleterious mutation model of molecular evolution
Eyre-Walker, A
Keightley, PD
Smith, NGC
Gaffney, D
[J]. MOLECULAR BIOLOGY AND EVOLUTION, 2002, 19 (12) : 2142 - 2149
[8] FELSENSTEIN J, 1985, EVOLUTION, V39, P783, DOI 10.1111/j.1558-5646.1985.tb00420.x
[9] RAPID PRODUCTION OF FULL-LENGTH CDNAS FROM RARE TRANSCRIPTS - AMPLIFICATION USING A SINGLE GENE-SPECIFIC OLIGONUCLEOTIDE PRIMER
FROHMAN, MA
DUSH, MK
MARTIN, GR
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (23) : 8998 - 9002
[10] Hagenblad J, 2002, GENETICS, V161, P289

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