Beyond Stereospecificity: Liquids and Mesoscale Organization of Cytoplasm

被引：135

作者：

Hyman, Anthony A. ^{[1
]}

Brangwynne, Clifford P. ^{[2
]}

机构：

[1] Max Planck Inst Mol Cell Biol & Genet, D-01307 Dresden, Germany

[2] Princeton Univ, Dept Chem & Biol Engn, Princeton, NJ 08544 USA

来源：

DEVELOPMENTAL CELL | 2011年 / 21卷 / 01期

关键词：

NUCLEOLI;

D O I：

10.1016/j.devcel.2011.06.013

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The cytoplasm is not a homogenous solution but instead consists of large dynamic assemblies that arise from transient molecular interactions. Some of these structures have been shown to represent liquid droplets of concentrated protein and RNA. Liquid phase separation of cytoplasm may be a fundamental principle of cytoplasmic organization.

引用

页码：14 / 16

页数：3

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