Model studies on total synthesis of the chartellines, spirocyclic β-lactam alkaloids from a marine bryozoan

被引：47

作者：

Lin, XC ^{[1
]}

Weinreb, SM ^{[1
]}

机构：

[1] Penn State Univ, Dept Chem, University Pk, PA 16802 USA

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 14期

基金：

美国国家科学基金会;

关键词：

Staudinger cycloadditions; azetidinones; imines; alkaloids; marine metabolites;

D O I：

10.1016/S0040-4039(01)00270-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A chartelline alkaloid model system containing a spirocyclic beta -lactam moiety and alpha,beta -unsaturated imine has been constructed from isatin using a Staudinger imine-ketene cycloaddition and an addition to an N-activated gamma -lactam as key steps. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：2631 / 2633

页数：3

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