Mild regeneration of the carboxylic group of amino acid alkyl esters by aqueous methanolic sodium hydrogen carbonate via 5-oxazolidinones

被引：7

作者：

Allevi, P

Anastasia, M

机构：

[1] Univ Milan, Dipartimento Med Chirurg & Odontoiatria, I-20142 Milan, Italy

[2] Univ Milan, Dipartimento Chim Biochim & Biotecnol Med, I-20133 Milan, Italy

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 41期

关键词：

D O I：

10.1016/j.tetlet.2003.08.028

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple racemization-free procedure allows the regeneration of the carboxylic acid group of amino acid alkyl esters by way of an intermediate 5-oxazolidinone which is hydrolyzed by treatment with sodium hydrogen carbonate in aqueous methanol. (C) 2003 Published by Elsevier Ltd.

引用

收藏

页码：7663 / 7665

页数：3

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