Alkane hydroxylation by a nonheme iron catalyst that challenges the heme paradigm for oxygenase action

被引：165

作者：

Company, Anna ^{[1
,2
,3
,4
]}

Gomez, Laura ^{[3
,4
]}

Gueell, Mireia ^{[3
,4
]}

Ribas, Xavi ^{[3
,4
]}

Luis, Josep M. ^{[3
,4
]}

Que, Lawrence, Jr. ^{[1
,2
]}

Costas, Miquel ^{[3
,4
]}

机构：

[1] Univ Minnesota, Dept Chem, Minneapolis, MN 55455 USA

[2] Univ Minnesota, Ctr Metal Biocatalysis, Minneapolis, MN 55455 USA

[3] Univ Girona, Dept Quim, E-17017 Girona, Spain

[4] Univ Girona, Inst Quim Computac, E-17017 Girona, Spain

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 129卷 / 51期

关键词：

D O I：

10.1021/ja077761n

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A nonheme iron catalyst catalyzed stereoselective oxidation of alkanes with H2O2 with remarkable efficiency and exhibiting an unprecedented high incorporation of water into the oxidized products. The present results challenge the canonical description of oxygenases, the standard oxo-hydroxo tautomerism that applies to heme systems and serves as a precedent for alternative pathways for the oxidation of hydrocarbons at nonheme iron oxygenases.

引用

页码：15766 / +

页数：3

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