Diastereoselective synthesis of α,β-unsaturated systems

被引：12

作者：

Castelani, P ^{[1
]}

Comasseto, JV ^{[1
]}

机构：

[1] Univ Sao Paulo, Inst Quim, BR-05508900 Sao Paulo, Brazil

来源：

TETRAHEDRON | 2005年 / 61卷 / 09期

基金：

巴西圣保罗研究基金会;

关键词：

functionalized tellurides; cyanocuprates; alpha; beta-unsaturated esters; beta-unsaturated ketones; diastereoselective synthesis;

D O I：

10.1016/j.tet.2005.01.025

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Functionalized Z-vinylic tellurides were used in substitution reactions with lower order cyanocuprates leading to alpha, beta-unsaturated ketones and esters in good yields. In the case of acyclic tellurides, the product was obtained in high diastereoselectivity. The control of the stereoselectivity was achieved by simple change of the reaction temperature. (C) 2005 Elsevier Ltd. All rights reserved.

引用

页码：2319 / 2326

页数：8

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