Redox thermodynamics of cytochrome c in mixed water-organic solvent solutions

被引：20

作者：

Borsari, M

Bellei, M

Tavagnacco, C

Peressini, S

Millo, D

Costa, G

机构：

[1] Univ Modena & Reggio Emilia, Dept Chem, I-41100 Modena, Italy

[2] Univ Trieste, Dept Chem Sci, I-34127 Trieste, Italy

来源：

INORGANICA CHIMICA ACTA | 2003年 / 349卷

关键词：

cytochrome c; cyclic voltammetry; thermodynamic properties;

D O I：

10.1016/S0020-1693(03)00043-4

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Bovine heart cytochrome c was studied through cyclic voltammetry in mixed water-organic solvent solutions under different conditions of temperature and the thermodynamic properties DeltaS(rc)(o) and DeltaH(rc)(o) calculated by the dependence of Edegrees by temperature. The effect of the organic fraction of the solvent on the Edegrees values of the native cyt c was found to be determined mainly by the decrease in dielectric constant of the medium. Specific interactions on the protein surface do not seem to play a remarkable role. The thermodynamic properties changes induced by the organic fraction have been interpreted tentatively in terms of solvation properties of cytochrome c and structural features of the protein environment. (C) 2003 Elsevier Science B.V. All rights reserved.

引用

页码：182 / 188

页数：7

共 38 条

[1] Redox thermodynamics of the native and alkaline forms of eukaryotic and bacterial class I cytochromes c [J].