Movin' on through with Cdc2

被引：17

作者：

Juliano, R ^{[1
]}

机构：

[1] Univ N Carolina, Dept Pharmacol, Chapel Hill, NC 27599 USA

来源：

NATURE CELL BIOLOGY | 2003年 / 5卷 / 07期

关键词：

D O I：

10.1038/ncb0703-589

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Proteins that control the cell cycle would seem to have little to do with cell migration. However, a recent report indicates that Cdc2, a key cyclin-dependent kinase, can also enhance cell migration. Levels of Cdc2 are upregulated in cells that express high levels of the alpha(v)beta(3) integrin, a protein that has long been implicated in enhanced migration and invasion of tumour cells.

引用

页码：589 / 590

页数：3

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