Cell motility - Actin branches out

被引：21

作者：

Machesky, LM

Way, M

机构：

[1] MRC, Mol Cell Biol Lab, London WC1E 6BT, England

[2] European Mol Biol Lab, D-69117 Heidelberg, Germany

来源：

NATURE | 1998年 / 394卷 / 6689期

关键词：

D O I：

10.1038/28039

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Cell movement is mediated by dynamic networks of actin — monomers of actin polymerize into filaments near the plasma membrane. How are these actin structures organized? Two groups have found that a seven-protein complex, containing the actin-related proteins Arp2 and Arp3, is responsible for initiating and organizing an actin-based dynamic meshwork that forms protrusions at the leading edge of motile cells.

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页码：125 / 126

页数：2

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