Protein translation, 2007

被引：39

作者：

Kaeberlein, Matt

Kennedy, Brian K.

机构：

[1] Univ Washington, Dept Pathol, Seattle, WA 98195 USA

[2] Univ Washington, Dept Biochem, Seattle, WA 98195 USA

来源：

AGING CELL | 2007年 / 6卷 / 06期

关键词：

degradation; dietary restriction; longevity; proteotoxicity; ribosome; target of rapamycin; translation;

D O I：

10.1111/j.1474-9726.2007.00341.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Translation of RNA to protein is essential for life. It should perhaps not be surprising, therefore, that appropriate regulation of translation plays a key role in determining longevity. This Hot Topic article discusses papers published in the last year related to the importance of translation and its regulation by signaling through the target of rapamycin kinase, in modulating aging and age-associated diseases.

引用

收藏

页码：731 / 734

页数：4

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