STRAP:: editor for STRuctural Alignments of Proteins

被引:181
作者
Gille, C [1 ]
Frömmel, C [1 ]
机构
[1] Humboldt Univ, Fac Med, Inst Biochem, Charite, D-10117 Berlin, Germany
关键词
D O I
10.1093/bioinformatics/17.4.377
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
STRAP is a comfortable and extensible tool for the generation and refinement of multiple alignments of protein sequences. Various sequence ordered input file formats are supported. These are the SwissProt-, GenBank-, EMBL-, DSSP- PDB-, MSF-, and plain ASCII text format. The special feature of STRAP is the simple visualization of spatial distances of C-alpha-atoms within the alignment. Thus structural information can easily be incorporated into the sequence alignment and can guide the alignment process in cases of low sequence similarities. further STRAP is able to manage huge alignments comprising a lot of sequences. The protein viewers and modeling programs INSIGHT, RASMOL and WEBMOL are embedded into STRAP. STRAP is written in Java. The well-documented source code can be adapted easily to special requirements. STRAP may become the basis for complex alignment tools in the future.
引用
收藏
页码:377 / 378
页数:2
相关论文
共 10 条
  • [1] DINAMO: interactive protein alignment and model building
    Bentz, J
    Baucom, A
    Hansen, M
    Gregoret, LM
    [J]. BIOINFORMATICS, 1999, 15 (04) : 309 - 316
  • [2] Visualisation and integration of G protein-coupled receptor related information help the modelling: Description and applications of the Viseur program
    Campagne, F
    Jestin, R
    Reversat, JL
    Bernassau, JM
    Maigret, B
    [J]. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 1999, 13 (06) : 625 - 643
  • [3] THE RELATION BETWEEN THE DIVERGENCE OF SEQUENCE AND STRUCTURE IN PROTEINS
    CHOTHIA, C
    LESK, AM
    [J]. EMBO JOURNAL, 1986, 5 (04) : 823 - 826
  • [4] Analysis of structural and physico-chemical parameters involved in the specificity of binding between α-amylases and their inhibitors
    Da Silva, MCM
    de Sá, MFG
    Chrispeels, MJ
    Togawa, RC
    Neshich, G
    [J]. PROTEIN ENGINEERING, 2000, 13 (03): : 167 - 177
  • [5] GOEDE A, 2000, UNPUB FAST ALGORITHM
  • [6] Protein modelling for all
    Guex, N
    Diemand, A
    Peitsch, MC
    [J]. TRENDS IN BIOCHEMICAL SCIENCES, 1999, 24 (09) : 364 - 367
  • [7] SWISS-MODEL and the Swiss-PdbViewer: An environment for comparative protein modeling
    Guex, N
    Peitsch, MC
    [J]. ELECTROPHORESIS, 1997, 18 (15) : 2714 - 2723
  • [8] CINEMA - a novel colour interactive editor for multiple alignments (Reprinted from Gene, vol 221, pg GC57-GC63, 1998)
    Parry-Smith, DJ
    Payne, AWR
    Michie, AD
    Attwood, TK
    [J]. GENE, 1998, 221 (01) : GC57 - GC63
  • [9] RASMOL - BIOMOLECULAR GRAPHICS FOR ALL
    SAYLE, RA
    MILNERWHITE, EJ
    [J]. TRENDS IN BIOCHEMICAL SCIENCES, 1995, 20 (09) : 374 - 376
  • [10] WebMol - A Java']Java-based PDB viewer
    Walther, D
    [J]. TRENDS IN BIOCHEMICAL SCIENCES, 1997, 22 (07) : 274 - 275