Protein purification and function assignment of the epoxidase catalyzing the formation of fosfomycin

被引：85

作者：

Liu, PH

Murakami, K

Seki, T

He, XM

Yeung, SM

Kuzuyama, T

Seto, H

Liu, HW ^{[1
]}

机构：

[1] Univ Texas, Coll Pharm, Div Med Chem, Austin, TX 78712 USA

[2] Univ Texas, Dept Chem & Biochem, Austin, TX 78712 USA

[3] Univ Minnesota, Dept Chem, Minneapolis, MN 55455 USA

[4] Univ Tokyo, Inst Mol & Cellular Biosci, Bunkyo Ku, Tokyo 1130032, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2001年 / 123卷 / 19期

关键词：

D O I：

10.1021/ja004153y

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：4619 / 4620

页数：2

共 18 条

[1] Synthesis of enantiopure epoxides through biocatalytic approaches [J].

Archelas, A ;

Furstoss, R .

ANNUAL REVIEW OF MICROBIOLOGY, 1997, 51 :491-525

[2] Chemistry and biosynthesis of clavulanic acid and other clavams [J].

Baggaley, KH ;

Brown, AG ;

Schofield, CJ .

NATURAL PRODUCT REPORTS, 1997, 14 (04) :309-333

[3] A NOVEL GENETIC SYSTEM TO DETECT PROTEIN PROTEIN INTERACTIONS [J].

FIELDS, S ;

SONG, OK .

NATURE, 1989, 340 (6230) :245-246

[4]

HAMMERSCHMIDT F, 1990, LIEBIGS ANN CHEM, P1055

[5] LABELED REPRESENTATIVES OF A POSSIBLE INTERMEDIATE OF FOSFOMYCIN BIOSYNTHESIS IN STREPTOMYCES-FRADIAE - PREPARATION OF (R,S)-(2-HYDROXYPROPYL)PHOSPHONIC, (R,S)-(2-HYDROXY-[1,1-H-2(2)]PROPYL)PHOSPHONIC, (R)-(2-HYDROXY-[1,1-H-2(2)]PROPYL)PHOSPHONIC AND (S)-(2-HYDROXY-[1,1-H-2](2)PROPYL)PHOSPHONIC AND (R,S)-(2-[O-18]HYDROXYPROPYL)PHOSPHONIC ACID [J].

HAMMERSCHMIDT, F .

MONATSHEFTE FUR CHEMIE, 1991, 122 (05) :389-398

[6] 2-STEP EPOXIDATION OF HYOSCYAMINE TO SCOPOLAMINE IS CATALYZED BY BIFUNCTIONAL HYOSCYAMINE 6-BETA-HYDROXYLASE [J].

HASHIMOTO, T ;

MATSUDA, J ;

YAMADA, Y .

FEBS LETTERS, 1993, 329 (1-2) :35-39

[7] PHOSPHONOMYCIN, A NEW ANTIBIOTIC PRODUCED BY STRAINS OF STREPTOMYCES [J].

HENDLIN, D ;

STAPLEY, EO ;

JACKSON, M ;

WALLICK, H ;

MILLER, AK ;

WOLF, FJ ;

MILLER, TW ;

CHAIET, L ;

KAHAN, FM ;

FOLTZ, EL ;

WOODRUFF, HB .

SCIENCE, 1969, 166 (3901) :122-&

[8] CLONING AND NUCLEOTIDE-SEQUENCE OF FOSFOMYCIN BIOSYNTHETIC GENES OF STREPTOMYCES-WEDMORENSIS [J].

HIDAKA, T ;

GODA, M ;

KUZUYAMA, T ;

TAKEI, N ;

HIDAKA, M ;

SETO, H .

MOLECULAR & GENERAL GENETICS, 1995, 249 (03) :274-280

[9] MECHANISM OF ACTION OF FOSFOMYCIN (PHOSPHONOMYCIN) [J].

KAHAN, FM ;

KAHAN, JS ;

CASSIDY, PJ ;

KROPP, H .

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1974, 235 (MAY10) :364-386

[10] Cloning and expression in Escherichia coli of 2-hydroxypropylphosphonic acid epoxidase from the fosfomycin-producing organism, Pseudomonas syringae PB-5123 [J].

Kuzuyama, T ;

Seki, T ;

Kobayashi, S ;

Hidaka, T ;

Seto, H .

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 1999, 63 (12) :2222-2224

← 1 2 →