G-protein-coupled receptors: turn-ons and turn-offs

被引:239
作者
Carman, CV
Benovic, JL
机构
[1] Thomas Jefferson Univ, Kimmel Canc Inst, Dept Mol Pharmacol & Biochem, Philadelphia, PA 19107 USA
[2] Thomas Jefferson Univ, Kimmel Canc Inst, Dept Microbiol & Immunol, Philadelphia, PA 19107 USA
关键词
D O I
10.1016/S0959-4388(98)80058-5
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Advances in the study of G-protein-coupled receptor regulation have provided novel insights into the role of G-protein-coupled receptor kinases and arrestins in this process. Of particular interest are recent studies that have dramatically expanded the known cellular functions of these molecules to include roles in receptor endocytosis and activation of MAP kinase signalling pathways.
引用
收藏
页码:335 / 344
页数:10
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