Four experiments investigated the effect of the fundamental frequency (FO) contour on speech intelligibility against interfering sounds. Speech reception thresholds (SRTs) were measured for sentences with different manipulations of their FO contours. These manipulations involved either reductions in FO variation, or complete inversion of the FO contour. Against speech-shaped noise, a flattened FO contour had no significant impact on SRTs compared to a normal FO contour; the mean SRT for the flattened contour was only 0.4 dB higher. The mean SRT for the inverted contour, however, was 1.3 dB higher than for the normal FO contour. When the sentences were played against a single-talker interferer, the overall effect was greater, with a 2.0 dB difference between normal and flattened conditions, and 3.8 dB between normal and inverted. There was no effect of altering the FO contour of the interferer, indicating that any abnormality of the FO contour serves to reduce intelligibility of the target speech, but does not alter the masking produced by interfering speech. Low-pass filtering the FO contour increased SRTs; elimination of frequencies between 2 and 4 Hz had the greatest effect. Filtering sentences with inverted contours did not have a significant effect on SRTs. (c) 2007 Acoustical Society of America.