An update in neoadjuvant chemotherapy in cervical cancer

被引：71

作者：

Panici, Pieluigi Benedetti

Bellati, Filippo

Pastore, Maria

Manci, Natalina

Musella, Angela

Pauselli, Simona

Angelucci, Michela

Muzii, Ludovico

Angioli, Roberto

机构：

[1] Univ Roma La Sapienza, Inst Gynecol Perinatol & Child Hlth, I-00100 Rome, Italy

[2] Univ Roma La Sapienza, Dept Expt Med, Rome, Italy

[3] Campus Biomed Univ, Dept Gynecol, Rome, Italy

来源：

GYNECOLOGIC ONCOLOGY | 2007年 / 107卷 / 01期

关键词：

D O I：

10.1016/j.ygyno.2007.07.041

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

More than two decades have passed since neoadjuvant chemotherapy has been introduced in the clinical practice. After several pilot studies, randomized trials and meta-analysis have confirmed the validity of this therapeutic strategy and in particular of neoadjuvant chemotherapy followed by radical surgery. Several open questions still remain unanswered and in particular no standard drug regiment is unanimously accepted. In this paper we describe how this treatment has evolved since its original introduction in the early eighties and describe possible drug regimens with their supporting evidence that can be adopted by physicians worldwide.

引用

页码：S20 / S22

页数：3

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