Caspofungin in combination with amphotericin B against Candida glabrata

被引:23
作者
Barchiesi, F
Spreghini, E
Fothergill, AW
Arzeni, D
Greganti, G
Giannini, D
Rinaldi, MG
Scalise, G
机构
[1] Univ Politecn Marche, Ist Malattie Infett & Med Pubbl, Ancona, Italy
[2] Univ Politecn Marche, Ctr Gestione Presidenza Med & Chirurg, Ancona, Italy
[3] Univ Texas, Hlth Sci Ctr, Dept Pathol, San Antonio, TX 78284 USA
[4] S Texas Vet Hlth Care Syst, Audie Murphy Div, San Antonio, TX USA
关键词
D O I
10.1128/AAC.49.6.2546-2549.2005
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The effects of caspofungin combined with amphotericin B were investigated with Candida glabrata. Although in vitro experiments showed an indifferent interaction, the combination regimen was the only therapeutic approach yielding organ sterilization in a murine candidemia model.
引用
收藏
页码:2546 / 2549
页数:4
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