Lessons from the "Euro-Phospholipid" project

被引：28

作者：

Cervera, Ricard ^{[1
]}

机构：

[1] Hosp Clin Barcelona, Inst Clin Med & Dermatol, Barcelona, Catalonia, Spain

来源：

AUTOIMMUNITY REVIEWS | 2008年 / 7卷 / 03期

关键词：

antiphospholipid syndrome; antiphospholipid antibodies; anticardiolipin antibodies; lupus anticoagulant;

D O I：

10.1016/j.autrev.2007.11.011

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The "Euro-Phospholipid" project started in 1999 with a multicentre, consecutive and prospective design. A total cohort of 1000 patients with antiphospholipid syndrome (APS), derived from 13 countries (Belgium, Bulgaria, Denmark, France, Germany, Greece, Hungary, Israel, Italy, the Netherlands, Portugal, Spain and United Kingdom), has been followed since then by a European consortium that was created as part of the network promoted by the "European Forum on Antiphospholipid. Antibodies", a study group devoted to the development of multicentre projects with large populations of APS patients. This project allowed the identification of the prevalence and characteristics of the main clinical and immunological manifestations at the onset and during the evolution of APS and demonstrated that it is possible to recognize more homogeneous subsets of clinical significance. (C) 2007 Elsevier B.V. All rights reserved.

引用

页码：174 / 178

页数：5

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