Reconstitution and biochemical characterization of a new pyridoxal-5′-phosphate biosynthetic pathway

被引:102
作者
Burns, KE [1 ]
Xiang, Y [1 ]
Kinsland, CL [1 ]
McLafferty, FW [1 ]
Begley, TP [1 ]
机构
[1] Cornell Univ, Dept Chem & Chem Biol, Ithaca, NY 14853 USA
关键词
D O I
10.1021/ja042792t
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The substrates for Bacillus subtilis PLP synthase (YaaD and YaaE) are identified, and the first reconstitution of PLP biosynthesis using this pathway is described. Three partial reactions catalyzed by YaaD are also identified. Copyright © 2005 American Chemical Society.
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页码:3682 / 3683
页数:2
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