Viral immune evasion strategies and the underlying cell biology

被引:44
作者
Lorenzo, ME [1 ]
Ploegh, HL [1 ]
Tirabassi, RS [1 ]
机构
[1] Harvard Univ, Sch Med, Dept Pathol, Boston, MA 02115 USA
关键词
immune evasion; virus; cell biology; interferon; MHC I; NK cell;
D O I
10.1006/smim.2000.0290
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Evasion of the immune system by viruses is a well-suited field. It remains a challenge to understand how these viral tactics affect pathogenesis and the viral lifecycle. At the same time, the study of viral proteins involved in immune evasion has helped us to better understand a number of cellular processes at the molecular level. Here we review recent data on different viral tactics for immune evasion and highlight what these viral interventions might teach us about cell biology.
引用
收藏
页码:1 / 9
页数:9
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