Genital herpes

被引：469

作者：

Gupta, Rachna ^{[1
]}

Warren, Terri ^{[4
]}

Wald, Anna ^{[1
,2
,3
,5
]}

机构：

[1] Univ Washington, Dept Med, Seattle, WA USA

[2] Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA

[3] Univ Washington, Dept Lab Med, Seattle, WA 98195 USA

[4] Westover Hts Clin, Portland, OR USA

[5] Fred Hutchinson Canc Res Ctr, Program Infect Dis, Seattle, WA 98104 USA

来源：

LANCET | 2007年 / 370卷 / 9605期

关键词：

D O I：

10.1016/S0140-6736(07)61908-4

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Genital herpes is the main cause of genital ulcers worldwide; the prevalence of herpes simplex virus (HSV) type 2 infections in the general population ranges from 10% to 60%. Most genital herpes is caused by HSV-2, although HSV-1 accounts for about half of new cases in developed countries. The risk of HIV acquisition is three times higher in people with HSV-2. Neonatal herpes is an uncommon but serious complication of genital herpes. Most genital HSV-2 infections are unrecognised and undiagnosed; infected individuals, even with mild symptoms, shed HSV, and can infect sexual partners. Since clinical diagnosis is neither sensitive nor specific, virological and type-specific serological tests should be used routinely. Oral antiviral drugs for HSV infections are safe and effective and can be used both to treat episodes and to prevent recurrences. Antiviral treatment of the infected partners and condom use reduce the risk of sexual transmission of HSV-2.

引用

页码：2127 / 2137

页数：11

共 127 条

[1]

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