Acinetobacter baumannii:: emergence and spread in Israeli hospitals 1997-2002

被引：59

作者：

Paul, M

Weinberger, M

Siegman-Igra, Y

Lazarovitch, T

Ostfeld, I

Boldur, I

Samra, Z

Shula, H

Carmeli, Y

Rubinovitch, B

Pitlik, S

机构：

[1] Rabin Med Ctr, Dept Med & Infect Dis, IL-49100 Petah Tiqwa, Israel

[2] Tel Aviv Sourasky Med Ctr, Infect Dis Unit, Tel Aviv, Israel

[3] Tel Aviv Sourasky Med Ctr, Div Epidemiol, Tel Aviv, Israel

[4] Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, Israel

[5] Bar Ilan Univ, Ramat Gan, Israel

[6] Rabin Med Ctr, Infect Control Unit, Petah Tiqwa, Israel

来源：

JOURNAL OF HOSPITAL INFECTION | 2005年 / 60卷 / 03期

关键词：

Acinetobacter baumannii; nosocomial; bacteraemia; epidemiology; drug resistance;

D O I：

10.1016/j.jhin.2005.01.007

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The incidence of mutti-drug-resistant Acinetobacter baumannii infections (BSIs) increased two- to four-fold in three Israeli hospitals between 1997 and 2002, accounting for 3.5 18 % of all hospital-acquired BSIs. This was associated with increasing carbapenem resistance reaching 35-54 %, and by a dramatic increase in carbapenem consumption. Inhospital fatality rates ranged between 47 % and 58 % and were significantly higher than those seen with other nosocomial. Gram-negative pathogens. A. boumannii was not restricted to intensive care units, but had spread to all hospital wards. Multi-drug-resistant A. boumannii has the potential to reach endemicity in hospitals and warrants more vigorous and innovative efforts to limit its spread. (c) 2005 The Hospital Infection Society. Published by Elsevier Ltd. All rights reserved.

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页码：256 / 260

页数：5

相关论文

共 15 条

[1] Multidrug-resistant Acinetobacter baumannii [J].

Abbo, A ;

Navon-Venezia, S ;

Orly, HM ;

Krichali, T ;

Siegman-Igra, Y ;

Carmeli, Y .

EMERGING INFECTIOUS DISEASES, 2005, 11 (01) :22-29

[2] Acinetobacter spp, as nosocomial pathogens: Microbiological, clinical, and epidemiological features [J].

BergogneBerezin, E ;

Towner, KJ .

CLINICAL MICROBIOLOGY REVIEWS, 1996, 9 (02) :148-+

[3] Nosocomial bacteremia involving Acinetobacter baumannii in critically ill patients:: a matched cohort study [J].

Blot, S ;

Vandewoude, K ;

Colardyn, F .

INTENSIVE CARE MEDICINE, 2003, 29 (03) :471-475

[4] Resistance of gram-negative non-fermentative bacilli causing bloodstream infection, Vienna, 1996-2003 [J].

Daxboeck, F ;

Assadian, O ;

Blacky, A ;

Koller, W ;

Hirschl, AM .

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2004, 23 (05) :415-416

[5] Role of environmental cleaning in controlling an outbreak of Acinetobacter baumannii on a neurosurgical intensive care unit [J].

Denton, M ;

Wilcox, MH ;

Parnell, P ;

Green, D ;

Keer, V ;

Hawkey, PM ;

Evans, I ;

Murphy, P .

JOURNAL OF HOSPITAL INFECTION, 2004, 56 (02) :106-110

[6] Emerging importance of multidrug-resistant Acinetobacter species and Stenotrophomonas maltophilia as pathogens in seriously ill patients:: Geographic patterns, epidemiological features, and trends in the SENTRY Antimicrobial Surveillance Program (1997-1999) [J].

Gales, AC ;

Jones, RN ;

Forward, KR ;

Liñares, J ;

Sader, HS ;

Verhoef, J .

CLINICAL INFECTIOUS DISEASES, 2001, 32 :S104-S113

[7] Successful control of an Acinetobacter baumannii outbreak in a neonatal intensive care unit [J].

Melamed, R ;

Greenberg, D ;

Porat, N ;

Karplus, M ;

Zmora, E ;

Golan, A ;

Yagupsky, P ;

Dagan, R .

JOURNAL OF HOSPITAL INFECTION, 2003, 53 (01) :31-38

[8] Acinetobacter baumannii bacteremia:: Clinical and prognostic features [J].

Rodríguez-Baño, J ;

Pascual, A ;

Gálvez, J ;

Muniain, MA ;

Ríos, MJ ;

Martínez-Martínez, L ;

Pérez-Cano, R ;

Perea, EJ .

ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA, 2003, 21 (05) :242-247

[9] Acinetobacter baumannii at a tertiary-care teaching hospital in Jerusalem, Israel [J].

Simhon, A ;

Rahav, G ;

Shazberg, G ;

Block, C ;

Bercovier, H ;

Shapiro, M .

JOURNAL OF CLINICAL MICROBIOLOGY, 2001, 39 (01) :389-391

[10] Nosocomial multi-drug resistant Acinetobacter baumannii bloodstream infection:: risk factors and outcome with ampicillin-sulbactam treatment [J].

Smolyakova, R ;

Borer, A ;

Riesenberg, K ;

Schlaeffer, F ;

Alkan, M ;

Porath, A ;

Rimar, D ;

Almog, Y ;

Gilad, J .

JOURNAL OF HOSPITAL INFECTION, 2003, 54 (01) :32-38