A new catalytic conjugate addition/aldol strategy that avoids preformed metalated nucleophiles

被引：64

作者：

Subburaj, K ^{[1
]}

Montgomery, J ^{[1
]}

机构：

[1] Wayne State Univ, Dept Chem, Detroit, MI 48202 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2003年 / 125卷 / 37期

关键词：

D O I：

10.1021/ja0362048

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new conjugate addition/aldol strategy has been developed. Unlike conventional procedures that require metalation of the nucleophilic species, the procedure allows the direct coupling of aryl iodides, aldehydes, and acrylates in a nickel-catalyzed, organozinc-promoted process. Copyright © 2003 American Chemical Society.

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页码：11210 / 11211

页数：2

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