Lactobacillus acidophilus autolysins inhibit Helicobacter pylori in vitro

被引：103

作者：

Lorca, GL

Wadström, T

de Valdez, GF

Ljungh, Å

机构：

[1] Lund Univ, Dept Med Microbiol & Infect Dis, S-22362 Lund, Sweden

[2] CERELA, RA-4000 San Miguel De Tucuman, Tucuman, Argentina

来源：

CURRENT MICROBIOLOGY | 2001年 / 42卷 / 01期

关键词：

D O I：

10.1007/s002840010175

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Antibacterial activity of 17 strains of lactobacilli was tested against 10 strains of H. pylori. The inhibition observed was related to the acid production and the low pH attained. No relationship between CagA phenotype of H, pylori strains and tolerance to lactic acid was observed. In mixed cultures, L. acidophilus CRL 639 showed an autolytic behavior after 24 h of culture. At this moment, H. py[ori CCUG17874 showed a decrease of 2 log-cycle, and no viable count was detected after 48 h, The bactericidal effect of L. acidophilus CRL 639 in mixed cultures is related to a proteinaceous compound released after cell lysis.

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页码：39 / 44

页数：6

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