The Escherichia coli gene pool

被引：18

作者：

Dougan, G ^{[1
]}

Haque, A ^{[1
]}

Pickard, D ^{[1
]}

Frankel, G ^{[1
]}

O'Goara, P ^{[1
]}

Wain, J ^{[1
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Dept Biochem, Ctr Mol Microbiol & Infect, London SW7 2AZ, England

来源：

CURRENT OPINION IN MICROBIOLOGY | 2001年 / 4卷 / 01期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/S1369-5274(00)00170-3

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Wild Escherichia coli are superbly adapted to survive in the intestines of their mammalian hosts and in the environment. E. coli K12 derivative (MG1655) encodes 4288 potential genes that provide the background genetic framework of this species. Particular E. coli clonal types encode additional chromosomal and extrachromosomal genes that facilitate the ability of E. coli to adapt to new environments. These additional genes are often clustered, have related functions (for example, virulence-associated genes in pathogenicity islands) and may be integrated at specific sites on the E. coli chromosome.

引用

收藏

页码：90 / 94

页数：5

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