The outs and ins of transposition: From mu to kangaroo

被引：204

作者：

Curcio, MJ

Derbyshire, KM

机构：

[1] New York State Dept Hlth, Wadsworth Ctr, Div Infect Dis, Albany, NY 12201 USA

[2] New York State Dept Hlth, Wadsworth Ctr, Lab Dev Genet, Albany, NY 12201 USA

[3] SUNY Albany, Sch Publ Hlth, Dept Biomed Sci, Albany, NY 12201 USA

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2003年 / 4卷 / 11期

关键词：

D O I：

10.1038/nrm1241

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Transposons are ubiquitous in prokaryotic and eukaryotic organisms and are major determinants of genome structure. Transposition - the movement of discrete segments of DNA without a requirement for homology - occurs by a handful of mechanisms that are used over and over again in different combinations. Understanding these mechanisms provides an important key to unlocking the secrets of genome organization and evolution.

引用

页码：865 / 877

页数：13

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