Digital coding of amino acids based on hydrophobic index

被引:107
作者
Xiao, Xuan [1 ]
Chou, Kuo-Chen [2 ]
机构
[1] Jing De Zhen Ceram Inst, Dept Comp, Jing De Zhen 33300, Peoples R China
[2] Gordon Life Sci Inst, San Diego, CA 92130 USA
关键词
amino acid digital coding; hydrophobic index; sequence analysis; signal process; pseudo amino acid composition;
D O I
10.2174/092986607782110293
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Analysis of amino acid sequences can provide useful insights into the tertiary structures of proteins and their biological functions. One of the critical problems in amino acid analysis is how to establish a digital coding system to better reflect the properties of amino acids and their degeneracy. Based on the hydrophobic index, a one-to-one relationship has been established between the amino acid sequence and the digital signal process. Such a "bridge" will make it possible to apply all the existing powerful methods in the signal processing area to analysis of the amino acid sequences.
引用
收藏
页码:871 / 875
页数:5
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