Synthesis of the C/D/E and A/B rings of xestobergsterol-(A)

被引：30

作者：

Krafft, ME ^{[1
]}

Dasse, OA ^{[1
]}

Fu, Z ^{[1
]}

机构：

[1] Florida State Univ, Dept Chem, Tallahassee, FL 32306 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1999年 / 64卷 / 07期

关键词：

D O I：

10.1021/jo982319w

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

The A/B and the C/D/E rings of the xestobergsterol skeleton have been stereoselectively synthesized starting with testosterone and epiandrosterone, respectively. A deconjugative ketalization of the A-ring enone of testosterone provided a handle for functionalization of the B-ring. A stereoselective aldol condensation was used to incorporate the E-ring.

引用

页码：2475 / 2485

页数：11

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