Restoring blood pressure reperfused Wernicke's area and improved language

被引:69
作者
Hillis, AE
Barker, PB
Beauchamp, NJ
Winters, BD
Mirski, M
Wityk, RJ
机构
[1] Johns Hopkins Univ, Sch Med, Dept Neurol, Baltimore, MD 21205 USA
[2] Johns Hopkins Univ, Sch Med, Dept Radiol, Baltimore, MD 21205 USA
[3] Johns Hopkins Univ, Sch Med, Dept Anesthesiol & Crit Care Med, Baltimore, MD 21205 USA
[4] Johns Hopkins Univ, Dept Cognit Sci, Baltimore, MD 21205 USA
关键词
D O I
10.1212/WNL.56.5.670
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Longitudinal clinical and imaging data from a patient who sustained a left frontal-temporal stroke with hypoperfusion of the adjacent Wernicke's area are reported. Ris language deficits were partially ameliorated by pharmacologically increasing his blood pressure, and were exacerbated when blood pressure dropped. There was a striking temporal and statistical correlation between mean arterial pressure and language accuracy. MR perfusion imaging showed that language gains were accompanied by improved perfusion of Wernicke's area when mean arterial pressure was increased.
引用
收藏
页码:670 / 672
页数:3
相关论文
共 10 条
[1]   Prediction of stroke outcome with echoplanar perfusion- and diffusion-weighted MRI [J].
Barber, PA ;
Darby, DG ;
Desmond, PM ;
Yang, Q ;
Gerraty, RP ;
Jolley, D ;
Donnan, GA ;
Tress, BM ;
Davis, SM .
NEUROLOGY, 1998, 51 (02) :418-426
[2]  
Damasio H., 1989, Lesion analysis in neuropsychology
[3]   PHENYLEPHRINE-INDUCED HYPERTENSION REDUCES ISCHEMIA FOLLOWING MIDDLE CEREBRAL-ARTERY OCCLUSION IN RATS [J].
DRUMMOND, JC ;
OH, YS ;
COLE, DJ ;
SHAPIRO, HM .
STROKE, 1989, 20 (11) :1538-1544
[4]   Applications of diffusion-perfusion magnetic resonance imaging in acute ischemic stroke [J].
Fisher, M ;
Albers, GW .
NEUROLOGY, 1999, 52 (09) :1750-1756
[5]   MR perfusion imaging reveals regions of hypoperfusion associated with aphasia and neglect [J].
Hillis, AE ;
Barker, PB ;
Beauchamp, NJ ;
Gordon, B ;
Wityk, RJ .
NEUROLOGY, 2000, 55 (06) :782-788
[6]   Evaluation of early reperfusion and IV tPA therapy using diffusion- and perfusion-weighted MRI [J].
Marks, MP ;
Tong, DC ;
Beaulieu, C ;
Albers, GW ;
de Crespigny, A ;
Moseley, ME .
NEUROLOGY, 1999, 52 (09) :1792-1798
[7]   CORTICAL HYPOPERFUSION AS A POSSIBLE CAUSE OF SUBCORTICAL APHASIA [J].
OLSEN, TS ;
BRUHN, P ;
OBERG, RGE .
BRAIN, 1986, 109 :393-410
[8]   BLOOD-FLOW AND VASCULAR REACTIVITY IN COLLATERALLY PERFUSED BRAIN-TISSUE - EVIDENCE OF AN ISCHEMIC PENUMBRA IN PATIENTS WITH ACUTE STROKE [J].
OLSEN, TS ;
LARSEN, B ;
HERNING, M ;
SKRIVER, EB ;
LASSEN, NA .
STROKE, 1983, 14 (03) :332-341
[9]   Hyperacute stroke: Ultrafast MR imaging to triage patients prior to therapy [J].
Sunshine, JL ;
Tarr, RW ;
Lanzieri, CF ;
Landis, DMD ;
Selman, WR ;
Lewin, JS .
RADIOLOGY, 1999, 212 (02) :325-332
[10]   The Treatment of Brain Ischemia With Vasopressor Drugs [J].
Wise, Gary ;
Sutter, Robert ;
Burkholder, James .
STROKE, 1972, 3 (02) :135-140