Role of the cerebellum in exploration behavior

被引：63

作者：

Caston, J ^{[1
]}

Chianale, C

Delhaye-Bouchaud, N

Mariani, J

机构：

[1] Univ Rouen, Fac Sci, Lab Neurobiol Apprentissage, UPRES PSY CO 1780, F-76821 Mt St Aignan, France

[2] Inst Gustave Roussy, Villejuif, France

[3] Univ Paris 06, Dev Neurobiol Lab, Paris, France

[4] Univ Paris 06, Inst Neurosci, UMR CNRS 7624, Paris, France

来源：

BRAIN RESEARCH | 1998年 / 808卷 / 02期

关键词：

cerebellum; motivation; exploration; habituation; Lurcher mutant mouse;

D O I：

10.1016/S0006-8993(98)00847-6

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Compared to + / + mice, Lurcher (+ /Lc) mutant mice whose cerebellar cortex is lacking almost all Purkinje cells and granule cells, exhibit a low level of exploration; this deficit is not due to a low level of activity but to both a decreased motivation to explore a novel environment and to spatial deficits. The characteristics of exploration in cerebellectomized +/+ and S/Lc mice suggest that the cerebellum is involved not only in cognitive but also in motivational processes. (C) 1998 Elsevier Science B.V. All rights reserved.

引用

页码：232 / 237

页数：6

共 51 条

[1]

BERNTSON GG, 1982, PHYSIOL PSYCHOL, V10, P2

[2]

BERTHIER NE, 1986, EXP BRAIN RES, V63, P341

[3] STRUCTURAL AND QUANTITATIVE STUDIES ON THE NORMAL C3H AND LURCHER MUTANT MOUSE [J].