Conformational changes during kinesin motility

被引：110

作者：

Schief, WR ^{[1
]}

Howard, J ^{[1
]}

机构：

[1] Univ Washington, Dept Physiol & Biophys, Seattle, WA 98195 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 2001年 / 13卷 / 01期

关键词：

D O I：

10.1016/S0955-0674(00)00169-1

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Nucleotide-dependent movements of the head and neck of kinesin have been visualized by cryoelectron microscopy and have been inferred from single-molecule studies. Key predictions of the hand-over-hand model for dimeric kinesin have been confirmed, and a novel processivity mechanism for the one-headed, kinesin-related motor KIF1A has been discovered.

引用

页码：19 / 28

页数：10

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