Acute effects of cigarette smoking on the QT interval in healthy smokers

被引:23
作者
Andrássy, G
Szabo, A
Dunai, A
Simon, E
Nagy, T
Trummer, Z
Tahy, A
Varro, A
机构
[1] Nottingham Trent Univ, Dept Life Sci, Nottingham, England
[2] Univ Szeged, Dept Pharmacol & Pharmocotherapy, Szeged, Hungary
关键词
D O I
10.1016/S0002-9149(03)00678-7
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This study assesses the effect of a first cigarette smoked in the morning on the QT interval duration in healthy habitual smokers after not smoking overnight. This study demonstrates that although after cigarette smoking the QT(Bc) values increase, the QT(Fc) and QT(Lc) values remained unchanged, and an in-creased sympathetic response was evident. The discrepancies between,the results seen by different QT correction formulas emphasize the importance of selecting an accurate method for heart rate correction when evaluating and interpreting alterations in QT values. (C)2003 by Excerpta Medica, Inc.
引用
收藏
页码:489 / 492
页数:4
相关论文
共 20 条
[1]   QTC PROLONGATION MEASURED BY STANDARD 12-LEAD ELECTROCARDIOGRAPHY IS AN INDEPENDENT RISK FACTOR FOR SUDDEN-DEATH DUE TO CARDIAC-ARREST [J].
ALGRA, A ;
TIJSSEN, JGP ;
ROELANDT, JRTC ;
POOL, J ;
LUBSEN, J .
CIRCULATION, 1991, 83 (06) :1888-1894
[2]  
Bazett HC, 1920, HEART-J STUD CIRC, V7, P353
[3]  
BEXTON RS, 1986, BRIT HEART J, V55, P253
[4]   INFLUENCE OF THE AUTONOMIC NERVOUS-SYSTEM ON THE Q-T INTERVAL IN MAN [J].
BROWNE, KF ;
ZIPES, DP ;
HEGER, JJ ;
PRYSTOWSKY, EN .
AMERICAN JOURNAL OF CARDIOLOGY, 1982, 50 (05) :1099-1103
[5]  
CANALE-H J M, 1987, Archivos del Instituto de Cardiologia de Mexico, V57, P57
[6]   CIGARETTE-SMOKING IS ASSOCIATED WITH DOSE-RELATED AND POTENTIALLY REVERSIBLE IMPAIRMENT OF ENDOTHELIUM-DEPENDENT DILATION IN HEALTHY-YOUNG ADULTS [J].
CELERMAJER, DS ;
SORENSEN, KE ;
GEORGAKOPOULOS, D ;
BULL, C ;
THOMAS, O ;
ROBINSON, J ;
DEANFIELD, JE .
CIRCULATION, 1993, 88 (05) :2149-2155
[7]   The effects of cigarette smoking on the heterogeneity of ventricular repolarization [J].
Dilaveris, P ;
Pantazis, A ;
Gialafos, E ;
Triposkiadis, F ;
Gialafos, J .
AMERICAN HEART JOURNAL, 2001, 142 (05) :833-837
[8]   Association between heart rate-corrected QT interval and coronary risk factors in 2,894 healthy subjects (The DESIR study) [J].
Fauchier, L ;
Maison-Blanche, P ;
Forhan, A ;
D'Hour, A ;
Lépinay, P ;
Tichet, J ;
Vol, S ;
Coumel, P ;
Fauchier, JP ;
Balkau, B .
AMERICAN JOURNAL OF CARDIOLOGY, 2000, 86 (05) :557-+
[9]   CIGARETTE-SMOKING AND HEMOSTATIC FUNCTION [J].
FITZGERALD, GA ;
OATES, JA ;
NOWAK, J .
AMERICAN HEART JOURNAL, 1988, 115 (01) :267-271
[10]  
Fridericia LS., 1920, Acta Med Scand, V53, P469, DOI DOI 10.1111/J.0954-6820.1920.TB18266.X