The complete genome sequence of Chromobacterium violaceum reveals remarkable and exploitable bacterial adaptability

被引：221

作者：

de Almeida, DF ^{[1
]}

Hungria, M ^{[1
]}

Guimaräes, CT ^{[1
]}

Antonio, RV ^{[1
]}

Almeida, FC ^{[1
]}

de Almeida, LGP ^{[1
]}

de Almeida, R ^{[1
]}

Alves-Gomes, JA ^{[1
]}

Andrade, EM ^{[1
]}

Araripe, J ^{[1
]}

de Araújo, MFF ^{[1
]}

Astolfi, S ^{[1
]}

Azevedo, V ^{[1
]}

Baptista, AJ ^{[1
]}

Bataus, LAM ^{[1
]}

Batista, JD ^{[1
]}

Beló, A ^{[1
]}

van den Berg, C ^{[1
]}

Bogo, M ^{[1
]}

Bonatto, S ^{[1
]}

Bordignon, J ^{[1
]}

Brigido, MM ^{[1
]}

Brito, CA ^{[1
]}

Brocchi, M ^{[1
]}

Burity, HA ^{[1
]}

Camargo, AA ^{[1
]}

Cardoso, DD ^{[1
]}

Carneiro, NP ^{[1
]}

Cavada, BS ^{[1
]}

Chueire, LMO ^{[1
]}

Creczynski-Pasa, TB ^{[1
]}

da Cunha, NC ^{[1
]}

Fagundes, N ^{[1
]}

Falcao, CL ^{[1
]}

Fantinatti, F ^{[1
]}

Farias, LP ^{[1
]}

Felipe, MSS ^{[1
]}

Ferrari, LP ^{[1
]}

Ferro, JA ^{[1
]}

Ferro, MT ^{[1
]}

Franco, GR ^{[1
]}

de Freitas, NSA ^{[1
]}

Furlan, LR ^{[1
]}

Gazzinelli, RT ^{[1
]}

Gomes, EA ^{[1
]}

Gonçalves, PR ^{[1
]}

Grangeiro, TB ^{[1
]}

Grattapaglia, D ^{[1
]}

Grisard, EC ^{[1
]}

Hanna, ES ^{[1
]}

机构：

[1] Univ Chicago, Chicago, IL 60637 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2003年 / 100卷 / 20期

关键词：

D O I：

10.1073/pnas.1832124100

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Chromobacterium violaceum is one of millions of species of free-living microorganisms that populate the soil and water in the extant areas of tropical biodiversity around the world. Its complete genome sequence reveals (i) extensive alternative pathways for energy generation, (h) approximate to500 ORF's for transport-related proteins, (iii) complex and extensive systems for stress adaptation and motility, and (iv) widespread utilization of quorum sensing for control of inducible systems, all of which underpin the versatility and adaptability of the organism. The genome also contains extensive but incomplete arrays of ORF's coding for proteins associated with mammalian pathogenicity, possibly involved in the occasional but often fatal cases of human C violaceum infection. There is, in addition, a series of previously unknown but important enzymes and secondary metabolites including paraquat-inducible proteins, drug and heavy-metal-resistance proteins, multiple chitinases, and proteins for the detoxification of xenobiotics that may have biotechnological applications.

引用

页码：11660 / 11665

页数：6

共 64 条

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