Successive replacement of halogen atoms in 4,6-dihaloquinolines in cross-coupling reactions with arylboronic acids catalyzed by palladium and nickel complexes

被引：16

作者：

Beletskaya, IP ^{[1
]}

Tsvetkov, AV ^{[1
]}

Latyshev, GV ^{[1
]}

Lukashev, NV ^{[1
]}

机构：

[1] Moscow MV Lomonosov State Univ, Moscow 119992, Russia

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2003年 / 39卷 / 11期

基金：

俄罗斯基础研究基金会;

关键词：

Nickel; Organic Chemistry; Iodine; Chlorine; Palladium;

D O I：

10.1023/B:RUJO.0000013144.15578.2d

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Conditions were found where in 6-halo-4-quinolines (halogen = iodine, bromine, or chlorine) the halo-en atoms were replaced in succession by similar or different aryl groups in cross-coupling reactions with arylboric acids catalyzed by palladium and nickel complexes. Basing on successive Suzuki reaction a convenient procedure was developed for preparation of diarylquinolines that did not require isolation of the intermediate monoarylation product and afforded almost quantitative yields of diarylquinolines.

引用

页码：1660 / 1667

页数：8

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