Microbiology in the post-genomic era

被引：234

作者：

Medini, Duccio ^{[1
]}

Serruto, Davide ^{[1
]}

Parkhill, Julian ^{[2
]}

Relman, David A. ^{[3
]}

Donati, Claudio ^{[1
]}

Moxon, Richard ^{[4
]}

Falkow, Stanley ^{[3
]}

Rappuoli, Rino ^{[1
]}

机构：

[1] Novartis Vaccines & Diagnost, I-53100 Siena, Italy

[2] Wellcome Trust Sanger Inst, Cambridge CB10 1SA, England

[3] Stanford Univ, Dept Microbiol & Immunol, Stanford, CA 94305 USA

[4] Univ Oxford, John Radcliffe Hosp, Oxford OX3 9DU, England

来源：

NATURE REVIEWS MICROBIOLOGY | 2008年 / 6卷 / 06期

关键词：

D O I：

10.1038/nrmicro1901

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Genomics has revolutionized every aspect of microbiology. Now, 13 years after the first bacterial genome was sequenced, it is important to pause and consider what has changed in microbiology research as a consequence of genomics. In this article, we review the evolving field of bacterial typing and the genomic technologies that enable comparative analysis of multiple genomes and the metagenomes of complex microbial environments, and address the implications of the genomic era for the future of microbiology.

引用

页码：419 / 430

页数：12

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