Epigenetic mechanisms in Alzheimer's disease: progress but much to do

被引：18

作者：

Balazs, Robert ^{[1
,2
]}

Vernon, Jeffrey ^{[3
]}

Hardy, John ^{[1
,2
]}

机构：

[1] UCL Inst Neurol, Reta Lilla Weston Res Labs, London, England

[2] UCL Inst Neurol, Dept Mol Neurosci, London, England

[3] UCL Wolfson Inst Biomed Res, London, England

来源：

NEUROBIOLOGY OF AGING | 2011年 / 32卷 / 07期

关键词：

Alzheimer's disease; Genetics; Epigenetics; DNA methylation; Gene expression; AMYLOID PRECURSOR PROTEIN; DNA METHYLATION; HISTONE ACETYLATION; GENE-TRANSCRIPTION; MEMORY FORMATION; MOUSE MODEL; BRAIN; SIRT1; AGE; PROMOTER;

D O I：

10.1016/j.neurobiolaging.2011.02.024

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

The interesting review from Mastroeni and colleagues highlights recent progress on epigenetic analysis of Alzheimer's disease, but it also illustrates how much we still need to do. (C) 2011 Published by Elsevier Inc.

引用

页码：1181 / 1187

页数：7

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