Three novel and one new lignan, chamaecypanones A, B, obtulignolide and isootobanone from the heartwood of Chamaecyparis obtusa var. formosana

被引：20

作者：

Kuo, YH ^{[1
]}

Chen, CH ^{[1
]}

Chiang, YM ^{[1
]}

机构：

[1] Natl Taiwan Univ, Dept Chem, Taipei, Taiwan

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 38期

关键词：

anthrone; 3,4-secophenyltetrahydronaphthalene-type lignan; phenyltetrahydronaphthalene-type lignan; Chamaecyparis obtusa var. formosana; Mosher ester;

D O I：

10.1016/S0040-4039(01)01272-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three novel lignans, chamaecypanone A 1, chamaecypanone B 2, obtulignolide 4, and one new lignan, isootobanone 3, were isolated from the heartwood of Chamaecyparis obtusa var. formosana, and were elucidated on the basis of 2D NMR techniques. Compounds 1 and 2, derived from a phenyltetrahydronaphthalene-type lignan by cleavage and cyclization, are anthrone derivatives. Compound 3 is a phenyltetrahydronaphthalene-type lignan, and 4 is a 3,4-secophenyltetrahydronaphthalene-type lignan. The absolute configurations of 3 and otobanone 5 were elucidated by a modified Mosher's method. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：6731 / 6735

页数：5

共 10 条

[1]

KAFUKU KINZO, 1931, BULL CHEM SOC JAPAN, V6, P40, DOI 10.1246/bcsj.6.40

[2]

KUO YH, 1989, CHEM PHARM BULL, V37, P2310, DOI 10.1248/cpb.37.2310

[3]

Kuo YH, 1998, CHEM PHARM BULL, V46, P181, DOI 10.1248/cpb.46.181

[4]

KUO YH, 1993, CHEM PHARM BULL, V41, P1507