Analysis of the estrogenic activity of sewage treatment works and receiving waters using vitellogenin induction in fish as a biomarker

被引:58
作者
Solé, M [1 ]
Porte, C [1 ]
Barceló, D [1 ]
机构
[1] CSIC, Dept Environm Chem, IIQAB, ES-08034 Barcelona, Spain
关键词
endocrine disrupter; vitellogenin; nonylphenol; estrogen; progestogen; carp; Cyprinus carpio;
D O I
10.1016/S0165-9936(01)00055-3
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The increased incidence of estrogenic activity in freshwater systems in the vicinity of sewage treatment works and several kilometers downstream of these plants has been measured by the induction of male fish plasma vitellogenin (VTG). Studies have been carried out either with caging or by sampling wild fish: the second kind of study is more realistic environmentally and permits the detection of negative effects that take place in early life stages. Several attempts have been made to relate the increase in VTG in male fish to the presence of certain chemicals. Reported concentrations of nonylphenol and natural and/or synthetic estrogens present in the same stretches of the river where fish were caught are, in many cases, high enough to be responsible for the observed VTG induction. (C) 2001 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:518 / 525
页数:8
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