Description and prediction of peptide-MHC binding: the 'human MHC project'

被引：55

作者：

Buus, S ^{[1
]}

机构：

[1] Inst Med Microbiol & Immunol, DK-2200 Copenhagen N, Denmark

来源：

CURRENT OPINION IN IMMUNOLOGY | 1999年 / 11卷 / 02期

关键词：

D O I：

10.1016/S0952-7915(99)80035-1

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

MHC: molecules are crucially involved in controlling the specific immune system. They are highly polymorphic receptors sampling peptides from the cellular environment and presenting these peptides for scrutiny by immune cells. Recent advances in combinatorial peptide chemistry have improved the description and prediction of peptide-MHC binding. It is envisioned that a complete, mapping of human immune reactivities will be possible.

引用

页码：209 / 213

页数：5

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