Xnkx-2.1:: a homeobox gene expressed during early forebrain, lung and thyroid development in Xenopus laevis

被引：20

作者：

Hollemann, T ^{[1
]}

Pieler, T ^{[1
]}

机构：

[1] Univ Gottingen, Inst Biochem & Mol Cell BIol, D-37073 Gottingen, Germany

来源：

DEVELOPMENT GENES AND EVOLUTION | 2000年 / 210卷 / 11期

关键词：

nkx; forebrain; lung; thyroid; Xenopus laevis;

D O I：

10.1007/s004270000098

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Nkx-2.1 is a member of the vertebrate Nkx family of homeobox genes; it was originally identified as a tissue-specific regulator of thyroglobulin and thyroperoxidase gene transcription. Here we report on the embryonic expression of Xnkx-2.1, which is expressed in the presumptive forebrain from early neurulation onwards. In tadpole stage embryos Xnkx-2.1 transcripts are primarily detected in ventral forebrain, lung buds and thyroid anlage. Therefore, Xnkx-2.1 may be part of the genetic network that controls the early development of these organs.

引用

页码：579 / 581

页数：3

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