Generation of glycinyl radicals via a 1,5-hydrogen atom transfer reaction.: Applications to γ-lactam formation

被引：15

作者：

Rancourt, J ^{[1
]}

Gorys, V ^{[1
]}

Jolicoeur, E ^{[1
]}

机构：

[1] Boehringer Ingelheim Canada Ltd, Biomega Res Div, Laval, PQ H7S 2G5, Canada

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 30期

关键词：

cyclisation; lactams; peptide analogues/mimics; radical reactions;

D O I：

10.1016/S0040-4039(98)01042-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Glycinyl radicals can be generated using a simple protecting/radical translocating group and used in the preferential formation of trans-3,4-disubstituted gamma-lactams via a radical cyclisation reaction. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：5339 / 5342

页数：4

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