Computational methods of analysis of protein-protein interactions

被引:90
作者
Salwinski, L
Eisenberg, D
机构
[1] Univ Calif Los Angeles, UCLA DOE Inst Genom & Proteom, Howard Hughes Med Inst, Dept Chem & Biochem, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, Inst Mol Biol, Dept Biol Chem, Los Angeles, CA 90095 USA
关键词
D O I
10.1016/S0959-440X(03)00070-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Computational methods play an important role at all stages of the process of determining protein-protein interactions. They are used to predict potential interactions, to validate the results of high-throughput interaction screens and to analyze the protein networks inferred from interaction databases.
引用
收藏
页码:377 / 382
页数:6
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