Dynamic concentration of motors in microtubule arrays

被引：86

作者：

Nédélec, F

Surrey, T

Maggs, AC

机构：

[1] EMBL, D-69115 Heidelberg, Germany

[2] ESPCI, CNRS, PCT, F-75005 Paris, France

来源：

PHYSICAL REVIEW LETTERS | 2001年 / 86卷 / 14期

关键词：

D O I：

10.1103/PhysRevLett.86.3192

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

We present experimental and theoretical studies of the dynamics of molecular motors in microtubule arrays and asters. By solving a convection-diffusion equation we find that the density profile of motors in a two-dimensional aster is characterized by continuously varying exponents. Simulations are used to verify the assumptions of the continuum model. We observe the concentration profiles of kinesin moving in quasi-two-dimensional artificial asters by fluorescent microscopy and compare with our theoretical results.

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收藏

页码：3192 / 3195

页数：4

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