Occurrence of several acidic drugs in sewage treatment plants in Switzerland and risk assessment

被引：314

作者：

Tauxe-Wuersch, A ^{[1
]}

De Alencastro, LF ^{[1
]}

Grandjean, D ^{[1
]}

Tarradellas, J ^{[1
]}

机构：

[1] Ecole Polytech Fed Lausanne, Lab Environm Chem & Ecotoxicol, CH-1015 Lausanne, Switzerland

来源：

WATER RESEARCH | 2005年 / 39卷 / 09期

关键词：

pharmaceutical; non-steroidal anti-inflammatory drugs; lipid regulation agent metabolite; wastewater; sewage treatment plant;

D O I：

10.1016/j.watres.2005.03.003

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The occurrence and fate of five acidic drugs (Mefenamic acid, Ibuprofen, Ketoprofen, Diclofenac and Clofibric acid) were analysed in three sewage treatment plants (STP) over 4-7 consecutive days. The results point out that the five substances were persistent in wastewater effluents after municipal wastewater treatment. At the most, half of Mefenamic acid was eliminated. Ibuprofen was well removed (80%) by one sewage treatment plant. The removal of Ibuprofen is dependent on the residence time of wastewater in the STPs. A long raining period induce an important decrease of removal of Ibuprofen and Ketoprofen. Removal rates showed a great variability according to sewage treatment plants and types of treatments (e.g. biological, physico-chemical). The concentrations of Ibuprofen, Mefenamic acid and Diclofenac were relatively high in the effluents (150-2000 ng/l), showing a potential contamination of surface water. An environmental risk assessment is presented. Mefenamic acid seems to present a risk for the aquatic environment, with a ratio PEC/PNEC higher than one. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：1761 / 1772

页数：12

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