Leptin - A novel link between obesity, diabetes, cardiovascular risk, and ventricular hypertrophy

被引：69

作者：

Sader, S

Nian, M

Liu, P

机构：

[1] Univ Toronto, Heart & Stroke Richard Lewar Ctr Excellence, Toronto, ON, Canada

[2] Univ Toronto, Dept Physiol, Toronto, ON, Canada

[3] Univ Hlth Network, Div Cardiol, Toronto Gen Hosp, Toronto, ON, Canada

来源：

CIRCULATION | 2003年 / 108卷 / 06期

关键词：

editorials; hormones; obesity; diabetes mellitus; hypertrophy;

D O I：

10.1161/01.CIR.0000081427.01306.7D

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：644 / 646

页数：3

共 20 条

[1]

Agata J, 1997, AM J HYPERTENS, V10, P1171

[2] Disruption of leptin signaling contributes to cardiac hypertrophy independently of body weight in mice [J].

Barouch, LA ;

Berkowitz, DE ;

Harrison, RW ;

O'Donnell, CP ;

Hare, JM .

CIRCULATION, 2003, 108 (06) :754-759

[3] The OB protein (leptin) pathway - A link between adipose tissue mass and central neural networks [J].

Campfield, LA ;

Smith, FJ ;

Burn, P .

HORMONE AND METABOLIC RESEARCH, 1996, 28 (12) :619-632

[4] Splice variants of the OB receptor gene are differentially expressed in brain and peripheral tissues of mice [J].

Chen, SC ;

Kochan, JP ;

Campfield, LA ;

Burn, P ;

Smeyne, RJ .

JOURNAL OF RECEPTOR AND SIGNAL TRANSDUCTION RESEARCH, 1999, 19 (1-4) :245-266

[5] Modulation of insulin activities by leptin [J].

Cohen, B ;

Novick, D ;

Rubinstein, M .

SCIENCE, 1996, 274 (5290) :1185-1188

[6] LEPTIN LEVELS REFLECT BODY LIPID-CONTENT IN MICE - EVIDENCE FOR DIET-INDUCED RESISTANCE TO LEPTIN ACTION [J].

FREDERICH, RC ;

HAMANN, A ;

ANDERSON, S ;

LOLLMANN, B ;

LOWELL, BB ;

FLIER, JS .

NATURE MEDICINE, 1995, 1 (12) :1311-1314

[7] Pivotal role of nitric oxide in the control of blood pressure after leptin administration [J].

Frühbeck, G .

DIABETES, 1999, 48 (04) :903-908

[8] WEIGHT-REDUCING EFFECTS OF THE PLASMA-PROTEIN ENCODED BY THE OBESE GENE [J].

HALAAS, JL ;

GAJIWALA, KS ;

MAFFEI, M ;

COHEN, SL ;

CHAIT, BT ;

RABINOWITZ, D ;

LALLONE, RL ;

BURLEY, SK ;

FRIEDMAN, JM .

SCIENCE, 1995, 269 (5223) :543-546

[9] Leptin and leptin receptor mRNA and protein expression in the murine fetus and placenta [J].

Hoggard, N ;

Hunter, L ;

Duncan, JS ;

Williams, LM ;

Trayhurn, P ;

Mercer, JG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (20) :11073-11078

[10] Leptin receptors expressed on pancreatic beta-cells [J].

Kieffer, TJ ;

Heller, RS ;

Habener, JF .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1996, 224 (02) :522-527

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