Putrescine bisamides from Aglaia gigantea

被引：23

作者：

Duong, Tu Ngoc

Edrada, RuAngelie

Ebel, Rainer

Wray, Victor

Frank, Walter

Duong, Anh Tuan

Lin, Wen Han

Proksch, Peter

机构：

[1] Univ Dusseldorf, Inst Pharm Biol & Biotechnol, D-40225 Dusseldorf, Germany

[2] Helmholtz Ctr Infect Res, Dept Biol Struct, D-38124 Braunschweig, Germany

[3] Univ Dusseldorf, Inst Inorgan & Struct Chem, D-40225 Dusseldorf, Germany

[4] Peking Univ, Natl Res Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China

来源：

JOURNAL OF NATURAL PRODUCTS | 2007年 / 70卷 / 10期

关键词：

D O I：

10.1021/np070184w

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Phytochemical analysis of the leaves of Aglaia gigantea collected in Vietnam yielded three cinnamoyl putrescine bisamide derivatives, which included the known compound dasyclamide (1), as well as two new natural products, gigantamide A (2) and grandiamide D (3). In this study, the structure of dasyclamide (1) was confirmed by X-ray crystallography. The structures of the two new alkaloids, gigantamide A (2) and grandiamide D (3), were elucidated through extensive I D and 2D NMR spectroscopy and analysis of their mass spectrometric (ESIMS, HRQTOFMS) data. The absolute configuration of grandiamide D (3) was determined via Mosher ester derivatization.

引用

页码：1640 / 1643

页数：4

共 18 条

[1] Bisamides, lignans, triterpenes, and insecticidal cyclopenta[b]benzofurans from Aglaia species [J].