Central visfatin causes orexigenic effects in chicks

被引:41
作者
Cline, Mark A. [1 ]
Nandar, Wint [1 ]
Prall, Brian C. [1 ]
Bowden, Christie N. [1 ]
Denbow, D. Michael [2 ]
机构
[1] Radford Univ, Dept Biol, Radford, VA 24142 USA
[2] Virginia Polytech Inst & State Univ, Univ Blacksburg, Dept Anim & Poultry Sci, Blacksburg, VA 24061 USA
关键词
appetite; chick; lateral hypothalamus; visfatin;
D O I
10.1016/j.bbr.2007.08.016
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Intracerebroventricular injection of visfatin caused increased feed intake and pecking efficiency, but did not affect water intake in chicks. Visfatin-treated chicks had increased c-Fos immunoreactivity in the lateral hypothalamus, decreased reactivity in the ventromedial hypothalamus and the dorsomedial hypothalamus, infundibular nucleus, periventricular nucleus, paraventricular nucleus were not affected. A low dose of visfatin increased locomotion. We conclude that intracerebroventricular injection of visfatin causes orexigenic effects in chicks. (C) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码:293 / 297
页数:5
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