Topical Therapies for Pruritus

被引：85

作者：

Elmariah, Sarina B. ^{[2
]}

Lerner, Ethan A. ^{[1
,2
]}

机构：

[1] Massachusetts Gen Hosp, Dept Dermatol, Cutaneous Biol Res Ctr, Boston, MA 02129 USA

[2] Harvard Univ, Sch Med, Cambridge, MA 02138 USA

来源：

SEMINARS IN CUTANEOUS MEDICINE AND SURGERY | 2011年 / 30卷 / 02期

基金：

美国国家卫生研究院; 比尔及梅琳达.盖茨基金会;

关键词：

STABILIZED ATOPIC-DERMATITIS; PIMECROLIMUS CREAM 1-PERCENT; 3; MU-G/G; TACROLIMUS OINTMENT; PEDIATRIC-PATIENTS; DOUBLE-BLIND; HUMAN SKIN; CALCINEURIN INHIBITORS; BRACHIORADIAL PRURITUS; INTRACTABLE PRURITUS;

D O I：

10.1016/j.sder.2011.04.008

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100227 [皮肤病学];

摘要：

Itch, or pruritus, is the predominant symptom associated with acute and chronic cutaneous disease, and in some cases may be debilitating. To date, there is no single universally effective anti-itch treatment. Because the pathophysiology of itch in most cutaneous or systemic disorders remains unclear, antipruritic therapy is often directed against a variety of targets, including the epidermal barrier, immune system, or the nervous system. Topical therapy is the mainstay of dermatologic management of acute or localized itch or in patients with contraindications to systemic therapies. This review will summarize current topical therapies to treat pruritus and discuss potential future therapies. Semin Cutan Med Surg 30:118-126 (C) 2011 Elsevier Inc. All rights reserved.

引用

页码：118 / 126

页数：9

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