Synthesis and configurational assignments of 3-substituted 2-deoxy-4-thio-D-erythro-pentofuranose derivatives

被引：8

作者：

Aitsir, H

Fahmi, NE

Goethals, G

Ronco, G

Tber, B

Villa, P

Ewing, DF

Mackenzie, G

机构：

[1] UNIV PICARDIE,CHIM ORGAN & CINET LAB,F-80039 AMIENS,FRANCE

[2] UNIV HULL,SCH CHEM,KINGSTON HULL HU6 7RX,N HUMBERSIDE,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1996年 / 14期

关键词：

D O I：

10.1039/p19960001665

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new route is described to 1-O-acetyl-2-deoxy-4-thio-alpha,beta-D-erythro-pentofuranose derivatives starting from L-arabinose. This route is amenable to variation in the 3-substituent and the 3-O-benzoyl and 3-azido derivatives were obtained in 17 and 15% yields, respectively, making this procedure easily the most economical entry to 4'-thionucleosides. The anomeric configuration of these and other thiosugars is established unequivocally.

引用

页码：1665 / 1671

页数：7

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